Pregnancy Complications in a-Thalassemia (Hemoglobinopathy H): A Case Study. (27th May 2018)

• Record Type: Journal Article
• Authors: Politou, Marianna; Dryllis, Giorgos; Efstathopoulou, Maria; Valsami, Serena; Triantafyllou, Faidra-Evangelia; Tsaroucha, Athanasia; Kattamis, Antonios; Vlahos, Nikos F.
• Other Names: Monni Giovanni Academic Editor.
• Is Part Of: Case reports in obstetrics and gynecology. Volume 2018(2018)
• Publication Date: 2018-05-27
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; Obstetrics; Gynecology; Genital Diseases, Female; Generative organs, Female -- Diseases; Gynecology; Obstetrics; Electronic journals; Periodicals; Periodicals; 618
• DOI: 10.1155/2018/8532081
• Languages: English
• ISSNs: 2090-6684

Abstract

Abstract : Thalassemia intermedia (TI) is a clinical definition which represents a wide spectrum of thalassemia genotypes but mainly includes patients who do not require or only occasionally require transfusion. An uncommon case of a 32-year-old Greek woman, para 1, at the 22nd week + day 3 of gestation with thalassemia intermedia (she was splenectomized), where her pregnancy was complicated with portal vein thrombosis, splenic thrombosis, and partial HELLP, is described. This is a generally uncommon event in thalassemia intermedia. She had no transfusion as her hematologist consulted and she took anticoagulation therapy. Thus, we present for the first time in the literature a case of HbH a-thalassemia pregnant woman whose pregnancy was complicated with portal vein thrombosis, splenic vein thrombosis, and partial HELLP; she was treated with anticoagulation therapy and she had a successful outcome.