Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma. (10th November 2016)

• Record Type: Journal Article
• Authors: Kim, Se Won; Lee, Seung-Eun; Oh, Young Lyun; Kim, Seokhwi; Park, Sun Hee; Kim, Jae Hyeon
• Other Names: Kane Michael P. Academic Editor.
• Is Part Of: Case reports in endocrinology. Volume 2016(2016)
• Publication Date: 2016-11-10
• Subjects: Endocrinology -- Periodicals; Endocrinology -- Case studies -- Periodicals; Endocrine glands -- Diseases -- Periodicals; Endocrinology; Endocrine System Diseases; Endocrine glands -- Diseases; Endocrinology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.4
• DOI: 10.1155/2016/5731417
• Languages: English
• ISSNs: 2090-6501

Abstract

Abstract : Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. Here, we report an exceptional case of NICTH caused by nonfunctioning adrenocortical carcinoma in a 39-year-old male with recurrent hypoglycemia. The patient's serum IGF-II/IGF-I ratio had increased to 27.8. The serum level of the IGF-II/IGF-I ratio was normalized after removal of the tumor, and the hypoglycemic attacks no longer occurred after the operation.