Perry syndrome with progressive supranuclear palsy-like phenotype in a Portuguese family – Long-term clinical follow-up. (March 2021)

• Record Type: Journal Article
• Authors: Barreto, Rui Duarte; Rodrigues, Rita; Roriz, José Mário; Alonso, Isabel; Magalhães, Marina
• Is Part Of: Parkinsonism & related disorders. Volume 84(2021)
• Page Start: 74
• Page End: 76
• Publication Date: 2021-03
• Subjects: Parkinson's disease -- Periodicals; Movement disorders -- Periodicals; Movement Disorders -- Periodicals; Nerve Degeneration -- Periodicals; Nervous System Diseases -- Periodicals; Parkinson Disease -- Periodicals; Tremor -- Periodicals; Parkinson, Maladie de -- Périodiques; Parkinson's disease; 616.833
• DOI: 10.1016/j.parkreldis.2021.02.004
• Languages: English
• ISSNs: 1353-8020

Abstract

Highlights: Perry syndrome is caused by different DCTN1 gene mutations. Apathy, vertical gaze palsy, and falls may be initial symptoms, mimicking progressive supranuclear palsy. Weight loss and hypoventilation may be absent in early stages. Oculogyric crisis in Perry syndrome may respond to anticholinergics.