Breast cancer treatment delays by socioeconomic and health care access latent classes in Black and White women. Issue 22 (21st September 2020)

• Record Type: Journal Article
• Authors: Emerson, Marc A.; Golightly, Yvonne M.; Aiello, Allison E.; Reeder‐Hayes, Katherine E.; Tan, Xianming; Maduekwe, Ugwuji; Johnson‐Thompson, Marian; Olshan, Andrew F.; Troester, Melissa A.
• Is Part Of: Cancer. Volume 126:Issue 22(2020)
• Page Start: 4957
• Page End: 4966
• Publication Date: 2020-09-21
• Subjects: breast cancer -- treatment delay -- treatment duration -- latent class analysis -- racial disparities -- health care disparities; Cancer -- Periodicals; Cancer -- Cytopathology -- Periodicals; 616.99405
• DOI: 10.1002/cncr.33121
• Languages: English
• ISSNs: 0008-543X

Abstract

Abstract : Background: Breast cancer mortality is higher for Black and younger women. This study evaluated 2 possible contributors to disparities—time to treatment and treatment duration—by race and age. Methods: Among 2841 participants with stage I‐III disease in the Carolina Breast Cancer Study, we identified groups of women with similar patterns of socioeconomic status (SES), access to care, and tumor characteristics using latent class analysis. We then evaluated latent classes in association with treatment delay (initiation >60 days after diagnosis) and treatment duration (in quartiles by treatment modality). Results: Thirty‐two percent of younger Black women were in the highest quartile of treatment duration (versus 22% of younger White women). Black women experienced a higher frequency of delayed treatment (adjusted relative frequency difference [RFD], 5.5% [95% CI, 3.2%‐7.8%]) and prolonged treatment duration (RFD, 8.8% [95% CI, 5.7%‐12.0%]). Low SES was significantly associated with treatment delay among White women (RFD, 3.5% [95% CI, 1.1%‐5.9%]), but treatment delay was high at all levels of SES in Black women (eg, 11.7% in high SES Black women compared with 10.6% and 6.7% among low and high SES White women, respectively). Neither SES nor access to care classes were significantly associated with delayed initiation among Black women, but both low SES and more barriers were associated with treatment duration across both groups. Conclusions: Factors that influence treatment timeliness persist throughout the care continuum, with prolonged treatment duration being a sensitive indicator of differences by race, SES, and care barriers. Abstract : Economic and other barriers to care appear to compound across the continuum, with treatment duration representing a sensitive indicator of barriers to care. By developing an integrated view of multiple patient factors that contribute to duration, appropriate multidimensional interventions can be conceptualized to reduce racial mortality disparities.