Evaluation of a multi-slice spiral computed tomography perfusion for the prediction of the recurrence of gastric cancer. (25th July 2018)

• Record Type: Journal Article
• Authors: Li, Chun-Feng; Wang, Da-Peng; Xue, Ying-Wei
• Is Part Of: Future oncology. Volume 14:Number 19(2018)
• Page Start: 1953
• Page End: 1963
• Publication Date: 2018-07-25
• Subjects: blood flow -- blood volume -- gastric cancer -- multi-slice spiral computed tomography -- perfusion parameter -- recurrence -- Tumor, Node, Metastasis -- vascular thrombus; Oncology -- Periodicals; 616.99405
• DOI: 10.2217/fon-2016-0541
• Languages: English
• ISSNs: 1479-6694

Abstract

Aim: The study aimed to elucidate the value of multislice spiral computed tomography (MSCT) perfusion for the early prediction of gastric cancer (GC) recurrence.Methods: MSCT perfusion scans were performed to obtain values pertaining to blood flow (BF), blood volume (BV), mean transit time (MTT) and permeability surface (PS). Logistic regression analysis was employed to evaluate the risk factors of postoperative recurrence in GC.Results: The maximum diameter of GC has a positive relationship with PS. The maximum enhancement of GC was positively correlated with BF, blood volume and PS. PS, BF, vascular thrombus and Tumor, Node, Metastasis staging were found to be significant risk factors in relation to the recurrence of GC (p = 0.006, p = 0.002, p < 0.001).Conclusion: MSCT perfusion is strongly correlated with postoperative recurrence of GC, and PS and BF values, vascular thrombus and Tumor, Node, Metastasis staging were discovered as being prominent factors influencing the recurrence of GC. Graphical abstract: The aim of this study is to elucidate the association between multislice spiral computed tomography perfusion and postoperative recurrence of gastric cancer (GC). Our results suggest that multislice spiral computed tomography perfusion is strongly correlated with postoperative recurrence of GC, and permeability surface and blood flow values, vascular thrombus and Tumor, Node, Metastasis staging are prominent factors influencing the recurrence of GC.