Distribution of human papillomavirus genotypes (2014–2016) in women with genital warts at a sexually transmitted disease clinic in Beijing, China. (February 2018)

• Record Type: Journal Article
• Authors: Ma, Liang; Lu, Shuang; Jiang, Yongwei; Li, Min; Cong, Xiao; Cao, Yongtong
• Is Part Of: Future virology. Volume 13:Number 2(2018)
• Page Start: 111
• Page End: 117
• Publication Date: 2018-02
• Subjects: Beijing -- China -- distribution -- genital warts -- human papillomavirus -- HPV -- prevalence -- sexually transmitted disease -- subtype -- vaccines -- women; Virology -- Periodicals; Virus diseases -- Treatment -- Periodicals; 616.9101
• DOI: 10.2217/fvl-2017-0097
• Languages: English
• ISSNs: 1746-0794

Abstract

Aim: The aim of this study was to analyze the distribution of human papillomavirus (HPV) genotypes among women with genital warts in the Beijing region of China.Methods: A total of 350 women diagnosed with genital warts between 2014 and 2016 were analyzed by real-time polymerase chain reaction (PCR) to test for high-risk and low-risk HPV subtypes.Results: The results show that 52.6% (184/350) of cases were positive for HPV6+11. The three most common high-risk HPVs detected were HPV52, HPV16 and HPV58, detected in 12.0% (42/350), 10.6% (37/350) and 10.0% (35/350) of all cases, respectively.Conclusion: These results indicate that vaccines targeting HPV subtypes 6, 11, 16, 52 and 58 would have the greatest impact among sexually active women living in Beijing.