Nickel‐Catalysed Amination of Arenes and Heteroarenes. Issue 25 (1st July 2022)

• Record Type: Journal Article
• Authors: Philip, Rose Mary; Veetil Saranya, Padinjare; Anilkumar, Gopinathan
• Is Part Of: European journal of organic chemistry. Volume 2022:Issue 25(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-01
• Subjects: Dedicated with great respect to Prof. Dr. Vijay Nair on the occasion of his 80th birthday. -- Amination -- Anilines -- C−N coupling -- Nickel -- Photocatalysis; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202200184
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: C(sp 2 )−N cross‐coupling is one of the most powerful transformations in organic synthesis to construct highly ubiquitous anilines and aniline derivatives. The dominance of Pd‐ and Cu‐based catalytic systems is evident in the field for a long time. However, Ni‐catalysed methodologies to achieve this reaction have grown gradually as sustainable alternatives in the last two decades. Recent reports of highly applicable photocatalytic and electrochemical amination strategies sufficiently enhanced the potential of Ni‐catalysed aminations. This review summarizes the advancement of this cross‐coupling reaction as a general and efficient method over the last 5 years. Abstract : C−N coupling is a valuable method to access synthetically relevant nitrogen‐containing compounds such as anilines and aniline derivatives. In the present review, we have covered the developments in Ni‐catalysed amination of arenes and heteroarenes over the past 5 years.