Comparison of three prognostic models for predicting cancer-specific survival among patients with gastrointestinal stromal tumors. (February 2018)

• Record Type: Journal Article
• Authors: Oweira, Hani; Schmidt, Jan; Mehrabi, Arianeb; Kulaksiz, Hasan; Schneider, Paul; Schöb, Othmar; Giryes, Anwar; Abdel-Rahman, Omar
• Is Part Of: Future oncology. Volume 14:Number 4(2018)
• Page Start: 379
• Page End: 389
• Publication Date: 2018-02
• Subjects: AFIP -- AJCC -- GIST -- NIH -- SEER; Oncology -- Periodicals; 616.99405
• DOI: 10.2217/fon-2017-0450
• Languages: English
• ISSNs: 1479-6694

Abstract

Aim: To evaluate the predictive value for cancer-specific survival of the models of the American Joint Committee on Cancer (AJCC) stage, NIH and Armed Forces Institute of Pathology (AFIP) among patients with gastrointestinal stromal tumors (GISTs).Methods: Surveillance, Epidemiology and End Results database (2010–2014) was accessed. Overall survival analysis and adjusted cancer-specific Cox regression hazard was calculated.Results: For gastric GISTs, concordance-index according to AJCC was 0.834; according to NIH was 0.833; according to AFIP was 0.836. Concordance-index for nongastric GISTs according to AJCC was 0.800, according to NIH was 0.801 and according to AFIP was 0.799.Conclusion: The performance of the three models is comparable with regards to cancer-specific survival prediction.