Serum Albumin to Creatinine Ratio and Short-Term Clinical Outcomes in Patients With ST-Elevation Myocardial Infarction. (October 2022)

• Record Type: Journal Article
• Authors: Turkyilmaz, Erdem; Ozkalayci, Flora; Birdal, Oğuzhan; Karagoz, Ali; Tanboga, Ibrahim H.; Tanalp, Ali Cevat; Oduncu, Vecih
• Is Part Of: Angiology. Volume 73:Number 9(2022)
• Page Start: 809
• Page End: 817
• Publication Date: 2022-10
• Subjects: albumin -- creatinine -- prognosis -- myocardial infarction -- serum albumin–creatinine ratio; Blood-vessels -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.13005
• DOI: 10.1177/00033197221089423
• Languages: English
• ISSNs: 0003-3197

Abstract

There is a lack of evidence regarding the short-term predictive value of serum albumin to creatinine ratio (sACR) in patients with ST-segment elevation myocardial infarction (STEMI). This study aims to investigate the relationship between sACR and short-term outcomes in these patients. We retrospectively enrolled 3057 patients with STEMI who underwent primary percutaneous coronary interventions (PCI) (median age was 58 years, and 74.3% were male). In-hospital mortality occurred in 114 (3.7%) patients. Contrast-induced nephropathy (CIN) was reported in 381 (12.4%) patients. During a 30-day follow-up, stent thrombosis (ST) occurred in 28 (.9%) patients and 30-day death in 147 (4.8%) patients. Multivariable logistic regression analysis reported that sACR was inversely associated with 30-day mortality (adjusted odds ratio (aOR): .51, 95% confidence interval (CI) .31–.82, P < .001). The sACR was also inversely associated with in-hospital mortality (aOR: .71, 95% CI .56–.90, P = .009), CIN (aOR: .60, 95% CI .52–.68, P < .001), congestive heart failure (CHF) (aOR: .64, 95% CI .47–.87, P = .007), and ST (aOR .61, 95% CI .41–.92, P = .001) at 30 days. Our findings suggest that sACR is inversely associated with short-term clinical outcomes in patients with STEMI after PCI.