Drug Delivery Systems: Hyperthermia‐Triggered On‐Demand Biomimetic Nanocarriers for Synergetic Photothermal and Chemotherapy (Adv. Sci. 11/2020). Issue 11 (10th June 2020)

• Record Type: Journal Article
• Authors: Gao, Junbin; Wang, Fei; Wang, Shuanghu; Liu, Lu; Liu, Kun; Ye, Yicheng; Wang, Zhen; Wang, Hong; Chen, Bin; Jiang, Jiamiao; Ou, Juanfeng; van Hest, Jan C. M.; Peng, Fei; Tu, Yingfeng
• Is Part Of: Advanced science. Volume 7:Issue 11(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-06-10
• Subjects: Science -- Periodicals; 505
• DOI: 10.1002/advs.202070060
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : In article number 1903642, Jan C. M. van Hest, Fei Peng, Yingfeng Tu, and co‐workers design an intelligent biomimetic nanocarrier, based on the crosslinking reaction of hyaluronic acid with the ancillary anticarcinogen cisplatin in the presence of doxorubicin‐decorated gold nanorods followed by cloaking of the cancer cell membrane. Upon NIR laser irradiation, in situ photothermal therapy is conducted which further induces hyperthermiatriggered on‐demand drug release from the nanogel reservoir to achieve a synergistic photothermal/chemo‐therapy. Cover image designed by Junbin Gao.