Serum urate goal attainment and associated factors in Chinese gout patients. Issue 8 (13th September 2020)

• Record Type: Journal Article
• Authors: Guo, Genkai; Dong, Chen; Yin, Rulan; Yang, Ying; Zhao, Rui; Wang, Yilin; Guo, Jiaxin; Zhou, Wei; Lu, Guoyuan
• Is Part Of: Psychology, health & medicine. Volume 25:Issue 8(2020)
• Page Start: 931
• Page End: 939
• Publication Date: 2020-09-13
• Subjects: Gout -- treat to target -- aging -- fat -- contributing factors; Medicine and psychology -- Periodicals; Clinical health psychology -- Periodicals; 610
• DOI: 10.1080/13548506.2019.1706751
• Languages: English
• ISSNs: 1354-8506

Abstract

ABSTRACT: We conducted a cross-sectional study with 350 gout patients to investigate serum urate acid (sUA) goal attainment (sUA < 360 μmol/L) and associated factors in Chinese gout patients in the Affiliated Hospital of Nantong University from August 2015 to September 2017. Descriptive statistics, health assessment questionnaire, global visual analog scale for general health and Gout Knowledge Questionnaire were calculated comparing patients at sUA goal or not at sUA goal. Univariate analysis and logistic regression models were applied to analyze data. The proportion of urate-lowering therapy (ULT) use was 61.2% (211/350). The mean ± standard deviation sUA of the participants was 475.07 ± 121.53 μmol/L. Only 17.4% of gout patients attain the serum urate goal, which also means 289(82.6%) patients cannot keep their sUA below the target of 360 μmol/L. The factors associated with sUA goal attainment including age, education level and ULT use. Among these, age, waist hip ratio, ULT, family history of cardiovascular disease was the predictor of sUA goal attainment. In conclusion, more than 80% of gout patients did not achieve sUA goal. Younger and fatter patients were more difficult to control the serum urate level.