The value of gamma glutamyltransferase in predicting myocardial infarction in patients with acute coronary syndrome. (January 2018)

• Record Type: Journal Article
• Authors: Valjevac, Amina; Rebic, Damir; Hamzic-Mehmedbasic, Aida; Sokolovic, Emir; Horozic, Dzan; Vanis, Nedim; Hadzovic-Dzuvo, Almira
• Is Part Of: Future cardiology. Volume 14:Number 1(2018)
• Page Start: 37
• Page End: 45
• Publication Date: 2018-01
• Subjects: acute coronary syndrome -- biomarker -- C-reactive protein -- cardiovascular disease -- gamma glutamyltransferase -- myocardial infarction -- receiver operating characteristic -- sensitivity -- specificity -- subclinical inflammation -- troponin; Cardiology -- Research -- Periodicals; 616.12005
• DOI: 10.2217/fca-2017-0033
• Languages: English
• ISSNs: 1479-6678

Abstract

Aim: To assess the utility of gamma-glutamyl transferase (GGT) and C-reactive protein (CRP) in predicting troponin elevation in patients with acute coronary syndrome.Patients: The total of 119 patients were divided into troponin-positive (n = 61) and troponin-negative (n = 58) patients.Results: CRP cut-off value ≥13.4 mg/l had the sensitivity of 68.1% and specificity of 62.5%, while the GGT cut-off value ≥61.5 IU/l had the sensitivity of 66.0% and specificity of 62.0% and combined use of both CRP and GGT had 71.4% sensitivity and 69.6% specificity in predicting troponin increase in acute coronary syndrome patients.Conclusion: GGT might be used as an adjuvant marker for risk assessment patients who present with chest pain and are suspected to have acute coronary syndrome.