Asperpenes D and E from the fungus Aspergillus sp. SCS-KFD66 isolated from a bivalve mollusk, Sanguinolaria chinensis. Issue 2 (1st February 2021)

• Record Type: Journal Article
• Authors: An, Chang-Liang; Kong, Fan-Dong; Li, Yan; Ma, Qing-Yun; Xie, Qing-Yi; Yuan, Jing-Zhe; Zhou, Li-Man; Dai, Hao-Fu; Yu, Zhi-Fang; Zhao, You-Xing
• Is Part Of: Journal of Asian natural products research. Volume 23:Issue 2(2021)
• Page Start: 117
• Page End: 122
• Publication Date: 2021-02-01
• Subjects: Marine-derived fungus -- Aspergillus sp. -- secondary metabolites; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2019.1709450
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Two new compounds named asperpenes D (1 ) and E (2 ) were isolated from the marine-derived fungus Aspergillus sp. SCS-KFD66. Their structures were determined on the basis of spectroscopic methods. Compound 2 represents the first natural product bearing a 2-substituted-5-oxo-4-phenyl-2, 5-dihydrofuran-3-carboxylic acid skeleton. All the compounds were tested for enzyme inhibitory activity against AChE and α-glucosidase and DPPH radical scavenging activity, respectively.