3D printed magnetic polymer composite hydrogels for hyperthermia and magnetic field driven structural manipulation. (August 2022)

• Record Type: Journal Article
• Authors: Ganguly, Sayan; Margel, Shlomo
• Is Part Of: Progress in polymer science. Volume 131(2022)
• Publication Date: 2022-08
• Subjects: Magnetic hydrogels -- Soft robotics -- Hyperthermia -- External magnetic field -- Additive manufacturing; χ susceptibility -- μ-CP microcontact printing -- 3D three dimensional -- Cs specific heat capacity -- Hc coercivity -- Ms magnetic moments -- Mr remanent magnetization -- Tc Curie temperature -- AC alternating current -- AMF alternating magnetic field -- ACG colloidal-patterned and cross-linked photonic hydrogel -- API active polymeric ingredients -- BC bacterial cellulose -- CMC carboxymethylcellulose -- CNT carbon nanotube -- DNA deoxyribonucleic Acid -- DDD drug delivery devices -- DDS drug delivery system -- DIW direct ink writing -- DOX doxorubicin -- DLP Digital light processing -- EHA 2-ethylhexyl acrylate -- EBL electron beam lithography -- EPR enhanced permeability and retention -- EMA European Medicines Agency -- FDA Food and Drug Administration -- FDM Fused Deposition Modeling -- FRP free radical polymerization -- GA gum acacia -- MA-CS Methacrylated chondroitin sulfate -- MCA magnetocrystalline anisotropy -- MENPs magnetoelectric nanoparticles -- HT hyperthermia -- IONPs iron oxide nanoparticles -- LRT linear response theory -- MIS minimally invasive surgery -- MNPs magnetic nanoparticles -- MHT magnetic hyperthermia -- MF magnetic field -- NPs nanoparticles -- NIPAM N-isopropylacrylamide -- PBA poly(butyl acrylate) -- PDA polydopamine -- PNIPAM poly(N-isopropylacrylamide) -- PAM pressure-assisted microsyringe -- PDLLA poly(D, L-lactide) -- PCL poly(lactic acid) -- PDI polydispersity index -- PHEMA 2-hydroxyethyl methacrylate -- HAP hydroxyapatite -- PEG polyethylene glycol -- PLA poly-lactic acid -- PVA polyvinyl alcohol -- LCST lower critical solution temperature -- RGD Arginylglycylaspartic acid -- SAR specific absorption rate -- SLP specific loss power -- SMPs shape memory polymers -- SLA stereolithography -- SPM superparamagnetism -- SPIONs superparamagnetic iron oxide nanoparticles -- TPP two-photon process -- UV ultraviolet; Polymers -- Periodicals; Polymerization -- Periodicals; Polymers -- Industrial applications -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; 547.7
• DOI: 10.1016/j.progpolymsci.2022.101574
• Languages: English
• ISSNs: 0079-6700

Abstract

Abstract: Magnetic hydrogels and soft composites have fueled the development of next generation biomimetic soft robotics due to their precise control and non-cytotoxic nature. Bare magnetic nanoparticles are difficult to regulate via remote controlling whereas, when these nanoparticles are arrested inside polymeric matrices, the whole system become an artificial soft mussel like integrated system. Concurrently, these polymeric magnetic soft materials are also prone to response of external magnetic field (static or oscillatory). Additive manufacturing via spatial assembly of polymeric precursors followed by actuation like behavior is quite a new manufacturing technique to fabricate magnetic soft materials. In this review, we focused on the magnetic nanoparticles and their entrapment into polymeric matrices and assessing their applicability in clinical (hyperthermia) as well as shape morphing behaviours. Both the behaviors are also amassed together to form dual responsive soft microbots. The techniques and their applications are elaborated in this review. Graphical abstract: Image, graphical abstract