Spinal cord involvement in two children with posterior reversible encephalopathy syndrome. (October 2017)

• Record Type: Journal Article
• Authors: Lucchesi, Maurizio; Mascalchi, Mario; Mussa, Federico; Favre, Claudio; Genitori, Lorenzo; Sardi, Iacopo
• Is Part Of: CNS oncology. Volume 6:Number 4(2017)
• Page Start: 287
• Page End: 290
• Publication Date: 2017-10
• Subjects: pediatric oncology -- PRES -- spinal cord involvement; Central nervous system -- Tumors -- Periodicals; 616.99481
• DOI: 10.2217/cns-2017-0003
• Languages: English
• ISSNs: 2045-0907

Abstract

Spinal cord involvement (SCI) is a rare feature of posterior reversible encephalopathy syndrome (PRES), especially in children. SCI is generally symptomatic, and may have a different outcome compared with encephalic localization of PRES. We reported about two cases of SCI in pediatric patients with PRES, after multimodal anticancer therapies, including radiotherapy, chemotherapy and targeted agents.