Cohort profile: the Liyang cohort study on chronic diseases and risk factors monitoring in China (Liyang Study). Issue 7 (18th July 2022)

• Record Type: Journal Article
• Authors: Zhou, Liang; Hu, Wei; Liu, Siyuan; Qiao, Yanan; He, Dingliu; Xiong, Shuting; Peng, Liuming; Cao, Lei; Wu, Ying; Sun, Na; Han, Qiang; Chu, Jiadong; Chen, Xuanli; Li, Tongxing; Feng, Zhaolong; He, Qida; Ke, Chaofu; Shen, Yueping
• Is Part Of: BMJ open. Volume 12:Issue 7(2022)
• Publication Date: 2022-07-18
• Subjects: epidemiology -- public health -- risk management; Medicine -- Research -- Periodicals; 610.72
• DOI: 10.1136/bmjopen-2022-060978
• Languages: English
• ISSNs: 2044-6055

Abstract

Abstract : Purpose: The Liyang cohort study on chronic diseases and risk factors monitoring in China (Liyang Study) is a prospective population-based study which aims to investigate and identify the determinants of the most prevalent chronic non-communicable diseases (NCDs) and to evaluate the impact of demographic characteristics, lifestyle, dietary habits, cognition, disability and NCDs on the health-related quality of life. Participants: Between March 2019 and June 2020, 10 056 individuals aged ≥18 years were administered a baseline survey through a multistage cluster random sampling in Liyang City, southern Jiangsu Province, China. Findings to date: The Liyang Study included detailed sociodemographic, anthropometric and health-related behaviour, common NCDs and blood sample information. Moreover, the study gathered a series of data on specific scales including the activities of daily living, instrumental activities of daily living, abbreviated mental test, Food Frequency Questionnaire and EuroQol 5-Dimensions 5-Levels Scale. Of the 10 056 participants, 52.92% (n=5322) were female and 92.26% (n=9278) came from rural areas. The mean age was 49.9±16.2 years. Men were more likely to have a higher level of education, annual income and a paid job than women (p<0.05). The top three overall most prevalent NCDs in the study were hypertension (18.06%, n=1815), digestive diseases (7.88%, n=791), and arthritis or rheumatism (5.28%, n=530). Women had a significantly higher prevalence of diabetes (5.46%, n=290 vs 4.42%, n=209, p=0.016) and arthritis (6.04%, n=321 vs 4.42%, n=209, p<0.001) than men, while the opposite was true for chronic lung diseases such as chronic obstructive pulmonary disease (1.37%, n=65 vs 0.92%, n=49, p=0.032) and chronic hepatic diseases (0.80%, n=38 vs 0.47%, n=25, p=0.035). Future plans: The current study will give valuable insights into the association between sociodemographic factors, health-related behaviour, diet, cognition, disability and genetic factors and the most prevalent NCDs among local community residents. Starting from 2022, a follow-up survey will be conducted every 3 years to further explore the causal relationship between the above factors and NCDs.