Avocado Consumption and Markers of Inflammation: Results From The Multi-ethnic Study of Atherosclerosis (MESA). (14th June 2022)

• Record Type: Journal Article
• Authors: Cheng, Feon; Ford, Nikki; Wood, Alexis; Tracy, Russell
• Is Part Of: Current developments in nutrition. Volume 6(2022)Supplement 1
• Page Start: 891
• Page End: 891
• Publication Date: 2022-06-14
• Subjects: Nutrition -- Periodicals; Nutritional Physiological Phenomena; Nutrition; Periodicals; Periodicals; Fulltext; Internet Resources; Periodicals; 612.3
• DOI: 10.1093/cdn/nzac067.011
• Languages: English
• ISSNs: 2475-2991

Abstract

Abstract: Objectives: Since an association of avocado consumption has been linked to a possible reduction in inflammation, we investigated associations between avocado consumption and markers of inflammation in a population-based multi-ethnic cohort (Multi-Ethnic Study of Atherosclerosis (MESA)). Methods: A food frequency questionnaire (FFQ) at MESA exam 1 was used to capture avocado/guacamole consumption. To calculate daily servings of avocado/guacamole, we used both frequency and serving size data from the FFQ. We classified participants into three consumer groups: rare or never (daily serving ≤ 0.03; less than 1 per month), medium (0.03 < daily serving < 0.082; ∼1–2 per month), and heavy (0.082 ≤ daily serving; more than 2–3 per month). Inflammation was estimated by natural log-transformed inflammatory biomarkers (CRP, IL-2, IL-6, homocysteine, fibrinogen, TNF-a soluble receptors). We used multivariate linear regression models to assess associations while accounting for age, sex, race/ethnicity, educational level, income, energy intake, smoking status, physical activity, diet quality, body mass index, and diabetes type. Results: Among 2, 183 MESA participants, the average age and BMI were 60.8 y ± 10.2 and 28.3kg/m2 ± 5.2, respectively, and 46% of the sample were men. Participants has self-reported Hispanic (40.7%), Caucasian (36.8%), African-American (15.5%), and Chinese (7%) ancestries. Over 60% had higher than a high school education and 41.7% make $50, 000 or more a year. 44% were categorized as rare of never, 31% as medium, and 25% as heavy avocado/guacamole consumers. When adjusted for relevant confounders, there were no significant differences among the three consumer groups for any inflammatory marker. Conclusions: In this cross-sectional study, we did not find that consumption of avocado/guacamole was associated with levels of inflammatory markers. Funding Sources: Supported by contracts HHSN268201500003I, N01-HC-95, 159, N01-HC-95, 160, N01-HC-95, 161, N01-HC-95, 162, N01-HC-95, 163, N01-HC-95, 164, N01-HC-95, 165, N01-HC-95, 166, N01-HC-95, 167, N01-HC-95, 168 and N01-HC-95, 169 from NHLBI, and by grants UL1-TR-000, 040, UL1-TR-001, 079, and UL1-TR-001, 420 from NCATS. The authors thank the other MESA investigators, staff, and participants for their valuable contributions. http://www.mesa-nhlbi.org provides a list of MESA investigators and institutions.