A comparative study of the HPLC-MS profiles and biological efficiency of different solvent leaf extracts of two African plants: Bersama abyssinica and Scoparia dulcis. Issue 3 (3rd April 2021)

• Record Type: Journal Article
• Authors: Sinan, Kouadio Ibrahime; Bene, Kouadio; Zengin, Gokhan; Diuzheva, Alina; Jekő, József; Cziáky, Zoltán; Picot-Allain, Carene Marie Nancy; Mollica, Adriano; Rengasamy, Kannan Rr; Mahomoodally, Mohamad Fawzi
• Is Part Of: International journal of environmental health research. Volume 31:Issue 3(2021)
• Page Start: 285
• Page End: 297
• Publication Date: 2021-04-03
• Subjects: Africa -- phyto-compounds -- natural agents -- therapeutics; Environmental health -- Periodicals; 363.7
• DOI: 10.1080/09603123.2019.1652885
• Languages: English
• ISSNs: 0960-3123

Abstract

ABSTRACT: In the present study, two medicinal plants from Africa, namely Bersama abyssinica Fresen. and Scoparia dulcis L., were extracted using ethyl acetate, methanol, and water. The antioxidant, enzyme (α-amylase, α-glucosidase, acetyl- and butyrylcholinesterase, lipase, and tyrosinase) inhibitory action, and phytochemical profiles of extracts of Bersama abyssinica and Scoparia dulcis were determined. The aqueous (180.62 and 61.81 mg gallic acid equivalent/g extract, for B. abyssinica and S. dulcis respectively) and methanol (75.21 and 57.81 mg rutin equivalent/g extract, for B. abyssinica and S. dulcis, respectively) extracts contained high concentrations of phenolic and flavonoids, respectively. The ethyl acetate extracts of both plants were potent inhibitors of α-glucosidase and tyrosinase. Several phytochemical groups were determined by HPLC-MS/MS. The study tend to suggest that B. abyssinica and S. dulcis are potential candidates for the development of novel therapeutical agents.