Are supermeres a distinct nanoparticle?. Issue 6 (3rd June 2022)

• Record Type: Journal Article
• Authors: Jeppesen, Dennis K.; Zhang, Qin; Franklin, Jeffrey L.; Coffey, Robert J.
• Is Part Of: Journal of extracellular biology. Volume 1:Issue 6(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-06-03
• Subjects: Coated vesicles -- Periodicals; Extracellular matrix -- Periodicals; Cytology -- Periodicals; Molecular biology -- Periodicals; Extracellular Vesicles; Extracellular Matrix; Coated vesicles; Cytology; Extracellular matrix; Periodical; Periodicals; 571.65
• DOI: 10.1002/jex2.44
• Languages: English
• ISSNs: 2768-2811

Abstract

Abstract: We have recently reported the discovery of a new distinct nanoparticle by ultracentrifugation of the supernatant of exomeres at 376, 000 x g for 16 hours. We termed the resulting pellet, supermeres (supernatant of exomeres). The Witwer team raised the legitimate question that these two membraneless nanoparticles may arise from a continuous population of extracellular particles. We have reviewed our data here and present additional analyses that reinforce supermeres as distinct nanoparticles.