Vitamin D levels are associated with epistaxis severity and bleeding duration in hereditary hemorrhagic telangiectasia. (April 2018)

• Record Type: Journal Article
• Authors: Weber, Lauren Marissa; McDonald, Jamie; Whitehead, Kevin
• Is Part Of: Biomarkers in medicine. Volume 12:Number 4(2018)
• Page Start: 365
• Page End: 371
• Publication Date: 2018-04
• Subjects: biomarker -- epistaxis -- hereditary hemorrhagic telangiectasia -- Osler–Weber–Rendu -- vitamin D; Biochemical markers -- Periodicals; 610.28
• DOI: 10.2217/bmm-2017-0229
• Languages: English
• ISSNs: 1752-0363

Abstract

Aim: To explore the association between vitamin D levels and mild versus severe epistaxis, as well as the overall epistaxis severity score (ESS) in patients with hereditary hemorrhagic telangiectasia.Patients & methods: A retrospective chart review of 198 patients was performed to explore the relationship between vitamin D levels and the ESS. Vitamin D levels were also compared with those with mild epistaxis to those with severe epistaxis.Results: A significant difference was found between patient's vitamin D levels and their associated ESS and duration of epistaxis. Patients with mild epistaxis had higher levels of vitamin D than patients with severe epistaxis.Conclusion: Vitamin D is associated with features of hereditary hemorrhagic telangiectasia including ESS, bleeding time and epistaxis severity.