Optimum treatment for primary intracranial Ewing sarcoma. Issue 3 (2nd July 2020)

• Record Type: Journal Article
• Authors: Howell, Sasha G.; Lyon, Kristopher A.; Garrett, David; Huang, Jason H.; Fonkem, Ekokobe
• Is Part Of: Proceedings. Volume 33:Issue 3(2020)
• Page Start: 430
• Page End: 432
• Publication Date: 2020-07-02
• Subjects: Chemotherapy -- Ewing sarcoma -- pineal region tumor -- radiation therapy; Medicine -- Periodicals; Medicine; Medicine -- Periodicals; Periodicals; Electronic journals; 616.005
• DOI: 10.1080/08998280.2020.1755199
• Languages: English
• ISSNs: 0899-8280

Abstract

Abstract: Ewing sarcoma (ES) is an aggressive, high-grade neuroectodermal neoplasm that frequently manifests in children and young adults. Although ES without osseous involvement most commonly involves paravertebral regions of the spine, it very rarely presents as a primary intracranial tumor. This report discusses a unique presentation of an adult extraosseous ES arising from the pineal region with extension into the third and fourth ventricles and multiple drop metastases to the spine. This case demonstrates the application of current chemotherapeutic and adjuvant management and offers insight into possible treatment modalities for metastasis in an atypical extraosseous ES involving the brain and spine.