Synthesis of Superparamagnetic Iron Oxide Nanoparticles Stabilized by Biocompatible Supramolecular β-Cyclodextrin for Biomedical Applications. (2019)

• Record Type: Journal Article
• Authors: Philip, Sherin; Kuriakose, Sunny
• Is Part Of: Materials today. Volume 11:Part 3(2019)
• Page Start: 1030
• Page End: 1035
• Publication Date: 2019
• Subjects: Fe2O3 -- β-Cyclodextrin -- Superparamagnetic -- Antibacterial -- Antifungal; Materials science -- Congresses -- Periodicals; 620.1
• DOI: 10.1016/j.matpr.2018.12.034
• Languages: English
• ISSNs: 2214-7853

Abstract

Abstract: Superparamagnetic iron oxide nanoparticles have always been a topic of significance in biomedical research due to their tremendous range of applications. The present study reports the synthesis of superparamagnetic Fe2 O3 nanoparticles by a simple NaBH4 -reduction, stabilised by supramolecular inclusion host β-cyclodextrin. The crystallite size was calculated from X-ray diffraction studies using Debye Scherrer equation and found to be in the range 14-23 nm. The antibacterial activity of the sample was studied against Vibrio cholerae and Clostridium botulinum using disc diffusion method. Antifungal activity was monitored against three fungal strains Candida auris, Trichophyton rubrum and Cryptococcus gatti using well diffusion method.