Bone fracture healing within a continuum bone remodelling framework. Issue 9 (4th July 2022)

• Record Type: Journal Article
• Authors: Schmidt, Ina; Albert, Jacob; Ritthaler, Marina; Papastavrou, Areti; Steinmann, Paul
• Is Part Of: Computer methods in biomechanics and biomedical engineering. Volume 25:Issue 9(2022)
• Page Start: 1040
• Page End: 1050
• Publication Date: 2022-07-04
• Subjects: Bone remodelling -- healing -- bone fracture -- femur head -- finite element method; Biomechanics -- Data processing -- Periodicals; Biomedical engineering -- Periodicals; Biomechanics -- Periodicals; Biomedical Engineering -- methods -- Periodicals; Computing Methodologies -- Periodicals; 612.7
• DOI: 10.1080/10255842.2021.1998465
• Languages: English
• ISSNs: 1025-5842

Abstract

Abstract: Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation.