Short and thick corpus callosum – the thin border between a minor anatomical variant to very poor outcome. (2nd September 2022)

• Record Type: Journal Article
• Authors: Bardin, Ron; Leibovitz, Zvika; Mashiach, Reuven; Ben-Sira, Liat; Salman, Lina
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 35:Number 17(2022)
• Page Start: 3305
• Page End: 3308
• Publication Date: 2022-09-02
• Subjects: Corpus callosum -- short -- Pitt–Hopkins syndrome -- ultrasound -- prenatal diagnosis; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2020.1818208
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: The corpus callosum (CC) is the largest commissure connecting the cerebral hemispheres. Its components are recognized sonographically at 18–20 GW and from that point forward, its growth can be assessed using nomograms for CC length and thickness according to gestational week. Prenatal diagnosis of agenesis of the CC has been reported comprehensively. On the contrary, information regarding findings as short or thick CC is very rare. Is short CC an expression of callosal dysgenesis or could it be a variant of the normal development when all its parts exist? We discuss this issue through this case report.