De Novo-Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome: An Animal Model for Severe/Critical COVID-19. (2nd July 2022)

• Record Type: Journal Article
• Authors: Andreotti, Sandro; Altmüller, Janine; Quedenau, Claudia; Borodina, Tatiana; Nouailles, Geraldine; Teixeira Alves, Luiz Gustavo; Landthaler, Markus; Bieniara, Maximilian; Trimpert, Jakob; Wyler, Emanuel
• Editors: Fraser, Bonnie
• Is Part Of: Genome biology and evolution. Volume 14:Number 7(2022)
• Publication Date: 2022-07-02
• Subjects: de novo -- whole-genome assembly -- Roborovski -- dwarf -- hamster -- Phodopus roborovskii; Genomics -- Periodicals; Genes -- Periodicals; 572.8605
• DOI: 10.1093/gbe/evac100
• Languages: English
• ISSNs: 1759-6653

Abstract

Abstract: The Roborovski dwarf hamster Phodopus roborovskii belongs to the Phodopus genus, one of the seven within Cricetinae subfamily. Like other rodents such as mice, rats, or ferrets, hamsters can be important animal models for a range of diseases. Whereas the Syrian hamster from the genus Mesocricetus is now widely used as a model for mild-to-moderate coronavirus disease 2019, Roborovski dwarf hamster shows a severe-to-lethal course of disease upon infection with the novel human coronavirus severe acute respiratory syndrome coronavirus 2.