Experimental evaluation of four-dimensional Magnetic Resonance Imaging for radiotherapy planning of lung cancer. (January 2021)

• Record Type: Journal Article
• Authors: Perkins, Terry; Lee, Danny; Simpson, John; Greer, Peter; Goodwin, Jonathan
• Is Part Of: Physics and imaging in radiation oncology. Volume 17(2021)
• Page Start: 32
• Page End: 35
• Publication Date: 2021-01
• Subjects: 4D-MRI -- 4D-CT -- Lung cancer -- radial VIBE -- Self-navigating; Radiotherapy -- Periodicals; Radiation dosimetry -- Periodicals; Cancer -- Imaging -- Periodicals; Oncology -- Periodicals; 615.842
• DOI: 10.1016/j.phro.2020.12.006
• Languages: English
• ISSNs: 2405-6316

Abstract

Abstract: Radiotherapy planning for lung cancer typically requires both 3D and 4D Computed Tomography (CT) to account for respiratory related movement. 4D Magnetic Resonance Imaging (MRI) with self-navigation offers a potential alternative with greater reliability in patients with irregular breathing patterns and improved soft tissue contrast. In this study 4D-CT and a 4D-MRI Radial Volumetric Interpolated Breath-hold Examination (VIBE) sequence was evaluated with a 4D phantom and 13 patient respiratory patterns, simulating tumour motion. Quantification of motion related tumour displacement in 4D-MRI and 4D-CT found no statistically significant difference in mean motion range. The results demonstrated the potential viability of 4D-MRI for lung cancer treatment planning.