Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt). (30th June 2022)

• Record Type: Journal Article
• Authors: Rahmawati, Novina; Syukri, Maimun; Darmawi, Darmawi; Zachreini, Indra; Zulfiani, Utari; Yusuf, Muhammad; Idroes, Rinaldi
• Other Names: Nilashi Mehrbakhsh Academic Editor.
• Is Part Of: TheScientificWorldjournal. Volume 2022(2022)
• Publication Date: 2022-06-30
• Subjects: Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1155/2022/2899462
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : This study aimed to study the inhibition activity of lactic acid bacteria probiotics deriving from Acehnese fermented Etawa goat's milk (yogurt) against Streptococcus pyogenes bacterial infection in rats ( Rattus norvegicus ). Haematological analysis of the rats' blood was performed on the following parameters: platelets, leukocytes, lymphocytes, neutrophils, and monocytes, where the data were further processed using ANOVA and Duncan's test with a confidence level of 95% (0.05). The results revealed that administering yogurt containing probiotics could reduce infections in the throats of rats caused by S. pyogenes . Based on the haematology examination, the probiotic yogurt could maintain the number of platelets, leukocytes, lymphocytes, neutrophils, and monocytes. Statistical significance was obtained when the infected rats were administered with a ±1.00 mL/day dose for seven days of treatment (p < 0.05 ).