Structural complexity of Konjac glucomannan and its derivatives governs the diversity and outputs of gut microbiota. (15th September 2022)

• Record Type: Journal Article
• Authors: Zhang, Yuan; Zhao, Yi; Yang, Wanfu; Song, Guangming; Zhong, Peizhe; Ren, Yuanyuan; Zhong, Geng
• Is Part Of: Carbohydrate polymers. Volume 292(2022)
• Publication Date: 2022-09-15
• Subjects: DF dietary fiber -- KGM konjac glucomannan -- DKGM Deacetylated konjac glucomannan -- KOGM Konjac oligo-glucomannan -- DD deacetylation degree -- SCFA short-chain fatty acid -- WAI water absorption index -- WSI water solubility index; Konjac Glucomannan -- Deacetylated Konjac Glucomannan -- Konjac Oligo-glucomannan -- Structural and physicochemical complexity -- Gut microbial consortia -- Metabolic outputs; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2022.119639
• Languages: English
• ISSNs: 0144-8617

Abstract

Abstract: Deacetylated Konjac Glucomannan (DKGM) and Konjac Oligo-glucomannan (KOGM) as two most widely used derivatives in food industry are structurally and physiologically distinct from Konjac glucomannan (KGM). However, the roles of their distinct structures and physicochemical properties in directing microbiota community and the following outcomes are not fully understood. This paper aims to build links between structural complexity of KGM and its derivatives and microbial metabolism. Results showed that structural alterations changed molecular chain aggregation and water binding ability, thus affected the susceptibility to enzymatic degradation, leading to the distinct microbial composition and outcomes profile. Explicitly, KOGM was distinctive in higher abundances of Catenibacterium and Megasphaera, and lacking Prevotella, which was additionally enriched by KGM and DKGM. KOGM, owned the same butyrate-dominant profile with KGM, was utilized fast. However, KGM possessed the highest fermentability. Severe deacetylation reduced fermentability and led DKGM to a propionate-dominant pattern. Graphical abstract: Unlabelled Image