An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019. Issue 6 (17th December 2020)

• Record Type: Journal Article
• Authors: Toovey, Oliver T. R.; Kulkarni, Priti; David, Joicy; Patel, Ayushi; Lai, Florence Y.; Burns, Joyce; Thompson, Catherine; Ellis, Joanna; Tang, Julian W.
• Is Part Of: Journal of medical virology. Volume 93:Issue 6(2021)
• Page Start: 3969
• Page End: 3973
• Publication Date: 2020-12-17
• Subjects: adenovirus -- community -- incidence -- keratoconjunctivitis -- nosocomial -- outbreak -- transmission -- UK; Virology -- Periodicals; 616
• DOI: 10.1002/jmv.26647
• Languages: English
• ISSNs: 0146-6615

Abstract

Abstract: We report a large epidemic ( n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye disease being present, these were not significantly different between the different AdV species, with similar rates of pseudomembrane formation and keratitis observed in patients with AdV species B as for those with AdV species D.