Large leiomyomatosis peritonealis disseminata after laparoscopic myomectomy: A case report with literature review. (2020)

• Record Type: Journal Article
• Authors: Yoshino, Yasunori; Yoshiki, Naoyuki; Nakamura, Reiko; Iwahara, Yuki; Ishikawa, Tomonori; Miyasaka, Naoyuki
• Is Part Of: International journal of surgery case reports. Volume 77(2020)
• Page Start: 866
• Page End: 869
• Publication Date: 2020
• Subjects: CT computed tomography -- FDA Food and Drug Administration -- LPD leiomyomatosis peritonealis disseminata -- MRI magnetic resonance imaging -- PM parasitic myoma -- US ultrasound; Leiomyomatosis peritonealis disseminata -- Morcellation -- Parasitic myoma -- Case report; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgery; Electronic journals; Periodicals; 617.005
• DOI: 10.1016/j.ijscr.2020.12.005
• Languages: English
• ISSNs: 2210-2612

Abstract

Highlights: Leiomyomatosis peritonealis disseminata (LPD) is a rare disease. LPD is associated with power morcellation during previous laparoscopic myomectomy. Long-term follow-up is necessary to detect LPD, which is not always symptomatic. Abstract: Introduction: Leiomyomatosis peritonealis disseminata (LPD) is a rare disease in which multiple leiomyomas are formed intraperitoneally. Several LPD cases were associated with laparoscopic myomectomy using power morcellators; however, LPD with a large tumor size remains extremely rare. We present a case of large LPD occurring after laparoscopic surgery. Presentation of case: A 26-year-old woman, gravida 0, underwent laparoscopic myomectomy with power morcellation in our institution. After 5 years, follow-up examination revealed pelvic tumors. Although we recommended resection, she refused and only wanted to be followed up. After 9 years from the first surgery, the tumors became symptomatic and were increasing in number (>10 nodules) and size (>15 cm). Needle biopsy detected leiomyoma. Computed tomography angiography showed that omental and mesenteric arteries were feeding the tumors. We performed laparotomy, and all the 19 tumors emerging from the omentum and mesenterium and weighing 7647 g in total were removed without injuring other organs. The maximum diameter of the largest tumor was 34 cm. The pathological diagnosis was nonmalignant LPD with leiomyoma. Discussion: Among all reported cases, our case had the largest LPD size. The tumors reached such a huge size because of two possible reasons: (1) they gradually grew asymptomatically over a long period from the time of diagnosis, and (2) they were fed by particularly large vessels, including the omental and mesenteric arteries. Conclusion: A large LPD is not always symptomatic. After a laparoscopic myomectomy, especially with power morcellation, long-term follow-up is necessary to detect LPD.