Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma. (21st June 2022)

• Record Type: Journal Article
• Authors: Khorasanchi, Adam; Benson, Zachary; Hall, Misty; Ebadirad, Nelya; Gharavi, Mohammad H.; Willard, Patrick; Chimzar, Miranda; McKay, John; Simmons, Gary; Yazbeck, Victor
• Other Names: Konstantopoulos Kostas Academic Editor.
• Is Part Of: Case reports in hematology. Volume 2022(2022)
• Publication Date: 2022-06-21
• Subjects: Hematology -- Periodicals; Hematology -- Case studies -- Periodicals; Blood -- Diseases -- Periodicals; Hematology; Hematologic Diseases; Blood -- Diseases; Hematology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.15
• DOI: 10.1155/2022/7139661
• Languages: English
• ISSNs: 2090-6560

Abstract

Abstract : Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided.