Commitment to dendritic cells and monocytes. (16th June 2021)
- Record Type:
- Journal Article
- Title:
- Commitment to dendritic cells and monocytes. (16th June 2021)
- Main Title:
- Commitment to dendritic cells and monocytes
- Authors:
- Ohteki, Toshiaki
Kawamura, Shunsuke
Onai, Nobuyuki - Abstract:
- Abstract: Dendritic cells (DCs) and monocytes are widely conserved immune cells in vertebrates that arise from hematopoietic stem cells via intermediate progenitors. The progenitors that strictly give rise to DCs or monocytes have been recently identified both in humans and in mice, thereby revealing their differentiation pathways. Advances in analysis technologies have further deepened our understanding of the development of DCs and monocytes from progenitor population-based to individual progenitor cell-based commitment. Since DC-committed progenitors, common DC progenitors (CDPs) and precursor conventional DCs (pre-cDCs) do not differentiate into monocytes, DCs are a distinct lineage from monocytes, although monocytes can acquire DC functions upon activation at tissues where they arrive.
- Is Part Of:
- International immunology. Volume 33:Number 12(2021)
- Journal:
- International immunology
- Issue:
- Volume 33:Number 12(2021)
- Issue Display:
- Volume 33, Issue 12 (2021)
- Year:
- 2021
- Volume:
- 33
- Issue:
- 12
- Issue Sort Value:
- 2021-0033-0012-0000
- Page Start:
- 815
- Page End:
- 819
- Publication Date:
- 2021-06-16
- Subjects:
- CDP -- CLP -- cMoP -- GMP
Immunology -- Periodicals
616.079 - Journal URLs:
- http://intimm.oxfordjournals.org/ ↗
http://ukcatalogue.oup.com/ ↗ - DOI:
- 10.1093/intimm/dxab031 ↗
- Languages:
- English
- ISSNs:
- 0953-8178
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4541.038930
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 22294.xml