Paraganglioma of the Urinary Bladder in a Dog. (July 2022)

• Record Type: Journal Article
• Authors: Hu, Shou-Ping; Zhang, Zhuo; Xiao, Fei; Huang, Jia-ni; Jiang, Yan; Mao, Dong-Sheng; Wang, Jing-Fei; He, Xi-Jun
• Is Part Of: Journal of comparative pathology. Volume 195(2022)
• Page Start: 1
• Page End: 6
• Publication Date: 2022-07
• Subjects: dog -- neoplasia -- paraganglioma -- urinary bladder; Veterinary pathology -- Periodicals; Veterinary therapeutics -- Periodicals; Pathology, Comparative -- Periodicals; Therapeutics -- Periodicals; Pathology, Veterinary -- Periodicals; 636.089607
• DOI: 10.1016/j.jcpa.2022.04.002
• Languages: English
• ISSNs: 0021-9975

Abstract

Summary: A 3-year-old male Bichon Frise developed lethargy, anorexia and haematuria. B-scan ultrasonography examination revealed a small, irregular, soft-textured mass in the bladder. Histopathologically, there was an incomplete fibrous pseudocapsule around the tumour tissue and although there was clear demarcation from the surrounding tissue, there was invasion of the capsule. Tumour cells proliferated in nests or cords of variable size, separated by fibrovascular tissue. The neoplastic cells were immunopositive for chromogranin A, synaptophysin and neuron-specific enolase, and electron microscopy revealed that they contained cytoplasmic secretory granules. On the basis of these findings, the tumour was diagnosed as a primary paraganglioma of the urinary bladder.