Application of cryopreserved autologous skin replantation in the treatment of degloving injury of limbs. Issue 7 (July 2022)

• Record Type: Journal Article
• Authors: Xu, Qingjia; Zhu, Lei; Wang, Gang; Sun, Yuliang; Wang, Juntao; Lin, Junhao; Pei, Yantao; Cui, Yidong; Liu, Ben; Yuan, Xiaoyu; Zhang, Hong; Zang, Chuanbao
• Is Part Of: Journal of plastic, reconstructive & aesthetic surgery. Volume 75:Issue 7(2022)
• Page Start: 2387
• Page End: 2440
• Publication Date: 2022-07
• Subjects: Skin graft -- Cryopreservation -- Degloving injury -- Tissue bank; Surgery, Plastic -- Great Britain -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Surgery, Plastic -- Great Britain -- Periodicals; 617.9505
• DOI: 10.1016/j.bjps.2022.04.006
• Languages: English
• ISSNs: 1748-6815

Abstract

Summary: Degloving injury is a common and intractable injury with the bone and tendon exposed and contamination, the stripped skin cannot be replanted immediately and will be discarded, although auto-graft is needed for subsequent wound repair. In this study, autologous skin cryopreservation technique was applied to the treatment of severe limb degloving injuries. The clinical data of 9 patients from January 2016 to December 2018 were analyzed retrospectively. Among the 9 cases, 1 case developed necrosis due to wound infection, and the rest survived 60–100%. The replanted cryopreserved skin were soft and resilient, with poor sensory recovery, varying degrees of discoloration and no hair growth. Cryopreservation provides more time for improving the wound and whole-body condition. The frozen skin had good quality and high survival rate. Our study can effectively use the degloving skin, reduce the damage of the donor area.