146  Epilepsy, deprivation and mortality in Wales 2005–2017. Issue 6 (27th May 2022)

• Record Type: Journal Article
• Authors: Daniels, H; Lacey, AS; Akbari, A; Fonferko-Shadrach, B; Hollinghurst, J; Rees, MI; Sawhney, IMS; Powell, HR; Kerr, MP; Owen Pickrell, W
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 93:Issue 6(2022)
• Page Start: A55
• Page End: A55
• Publication Date: 2022-05-27
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp-2022-ABN.177
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Background: Public Health England have recently reported that deaths associated with epilepsy are increasing and are associated with increased deprivation. We investigated comparable Welsh mortality trends and associations between epilepsy mortality and deprivation. Method: We used routinely-collected health data within the Secure Anonymised Information Linkage (SAIL) Databank. We recorded deaths associated with epilepsy (DAE), epilepsy recorded on death certificates, and deaths in people with epilepsy (DPWE), people with diagnoses of epilepsy and epilepsy prescriptions before death. We compared death rates in different deprivation deciles adjusting for epilepsy prevalence. Results: During 2005–2017 (41million patient-years) there were 2116 DAE and 7821 DPWE. DAE and DPWE increased from 4.3/100, 000/yr and 17.2/100, 000/yr in 2005–2007 to 5.7/100, 000/yr and 20.9/100, 000/yr in 2015–2017. The age-standardised mortality rates (ASMR) in 2006–2008 for DAE and DPWE were 5.3/100, 000/yr and 20/100, 000/yr respectively, in 2015–2017 they were 5.8/100, 000/yr and 20/100, 000/yr. DAE were not significantly associated with deprivation when adjusted for epilepsy prevalence. Conclusion: When adjusting for age, deaths associated wtih epilepsy and deaths in people with epilepsy did not increase significantly in Wales between 2005–2007 and 2015–2017. The association between dep- rivation and deaths associated with epilepsy appears to be explained by higher epilepsy prevalence in areas of higher deprivation. [e-mail]