Two new phenolic glucosides from marine-derived fungus Aspergillus sp. Issue 13 (1st July 2022)

• Record Type: Journal Article
• Authors: Wen, Huiling; Zang, Yi; Zhu, Qianheng; Ouyang, Sheng; Luo, Juanjuan; Luo, Nianhua; Zhu, Hucheng; Zhang, Yonghui
• Is Part Of: Natural product research. Volume 36:Issue 13(2022)
• Page Start: 3255
• Page End: 3261
• Publication Date: 2022-07-01
• Subjects: Aspergillus sp -- phenolic -- glucoside; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2020.1851226
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new phenolic glucosides, including a new O -glycoside (1 ) and a new C -glycoside (2 ), were isolated from a marine-derived fungus Aspergillus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of 1 was identified as β -D-glucose by comparison with an authentic sample via HPLC after acid hydrolysis and derivatization. All compounds were evaluated for their ability to inhibit LPS-induced NO production in RAW264.7 macrophages, but none of them displayed significant activity. Graphical Abstract: UF0001