Excited state lifetime modulation in semiconductor nanocrystals for super-resolution imaging. (3rd September 2022)

• Record Type: Journal Article
• Authors: Ghosh, Subhabrata; Hollingsworth, Jennifer A; Gallea, Jose Ignacio; Majumder, Somak; Enderlein, Jörg; Chizhik, Alexey I
• Is Part Of: Nanotechnology. Volume 33:Number 36(2022)
• Publication Date: 2022-09-03
• Subjects: super-resolution imaging -- semiconductor nanocrystals -- FLIM -- fluorescence lifetime imaging microscopy; Nanotechnology -- Periodicals; Nanotechnology -- Periodicals; Nanotechnology; Publications périodiques; Nanotechnologies; Periodicals; 620.5
• DOI: 10.1088/1361-6528/ac73a2
• Languages: English
• ISSNs: 0957-4484

Abstract

Abstract: We report on proof of principle measurements of a concept for a super-resolution imaging method that is based on excitation field density-dependent lifetime modulation of semiconductor nanocrystals. The prerequisite of the technique is access to semiconductor nanocrystals with emission lifetimes that depend on the excitation intensity. Experimentally, the method requires a confocal microscope with fluorescence-lifetime measurement capability that makes it easily accessible to a broad optical imaging community. We demonstrate with single particle imaging that the method allows one to achieve a spatial resolution of the order of several tens of nanometers at moderate fluorescence excitation intensity.