Hydroxyapatite for bone related applications derived from sea shell waste by simpleprecipitation method. Issue 2 (2nd April 2020)

• Record Type: Journal Article
• Authors: Suresh Kumar, C.; Dhanaraj, K.; Vimalathithan, R.M.; Ilaiyaraja, P.; Suresh, G.
• Is Part Of: Journal of Asian ceramic societies. Volume 8:Issue 2(2020)
• Page Start: 416
• Page End: 429
• Publication Date: 2020-04-02
• Subjects: Hydroxyapatite -- Precipitation method -- Antibacterial activity -- Hemolysis assay -- SBF analysis; Ceramics -- East Asia -- Periodicals; Materials science -- Periodicals; 620.1405
• DOI: 10.1080/21870764.2020.1749373
• Languages: English
• ISSNs: 2187-0764

Abstract

ABSTRACT: The nano-hydroxyapatite (NHAp), NHAp/PEG and NHAp/PVP have been derived from Clam shell by precipitation method. The presence of characteristic FTIR peaks and XRD planes indicates the formation of NHAp. Surface morphology of NHAp, NHAp/PEG and NHAp/PVP appeared to be flake, majorly hexagonal and rod clusters like structure, respectively. Sizes of the NHAp are in nanometer scale and size of NHAp/PVP is the lowest. The poor crystalline nature and high carbonate content presence in NHAp/PVP are assessed through crystallinity index, C/P ratio and CHNS analysis. EDX analysis shows the presence of HAp composition in NHAp. The calculated structural parameters expose that the NHAp/PVP shows favorable mechanical property. Good antibacterial activity is observed in NHAp/PVP against two bacteria strains. Hemolysis study also indicates that NHAp/PVP is non-hemolytic. Formation of complete apatite is found when NHAp/PVP immersed in SBF for 14 days. Thus, the NHAp/PVP derived from Clam shell may be useful for bone-related applications.