Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient. Issue 1 (1st January 2020)

• Record Type: Journal Article
• Authors: Sun, Jing; Zhu, Airu; Li, Heying; Zheng, Kui; Zhuang, Zhen; Chen, Zhao; Shi, Yongxia; Zhang, Zhaoyong; Chen, Si-bei; Liu, Xuesong; Dai, Jun; Li, Xiaobo; Huang, Shuxiang; Huang, Xiaofang; Luo, Ling; Wen, Liyan; Zhuo, Jianfen; Li, Yuming; Wang, Yanqun; Zhang, Lu; Zhang, Yanjun; Li, Fang; Feng, Liqiang; Chen, Xinwen; Zhong, Nanshan; Yang, Zifeng; Huang, Jicheng; Zhao, Jincun; Li, Yi-min
• Is Part Of: Emerging microbes & infections. Volume 9:Issue 1(2020)
• Page Start: 991
• Page End: 993
• Publication Date: 2020-01-01
• Subjects: COVID-19 -- urine -- transmission -- SARS-CoV-2 -- virus isolation; Medical microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.9041
• DOI: 10.1080/22221751.2020.1760144
• Languages: English
• ISSNs: 2222-1751

Abstract

ABSTRACT: SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its' own patient sera. Appropriate precautions should be taken to avoid transmission from urine.