Genome Sequence of the Human Opportunistic Fungus Arthrocladium fulminans (CBS 136243). Issue 6 (1st June 2020)

• Record Type: Journal Article
• Authors: Moreno, Leandro Ferreira; Menezes da Silva, Nickolas; Weiss, Vinicius Almir; de Fátima Costa, Flavia; Bittencourt, Juliana V; Macedo, Luciano Medina; Gomes, Renata R; Souza, Emanuel M; Vicente, Vania Aparecida; Stielow, Benjamin; de Hoog, Sybren
• Is Part Of: G3. Volume 10:Issue 6(2020)
• Page Start: 1817
• Page End: 1821
• Publication Date: 2020-06-01
• Subjects: black yeast -- Chaetothyriales -- Trichomeriaceae -- whole-genome sequencing; Genetics -- Research -- Periodicals; Genomics -- Periodicals; Genetics; Genomics; Genes; Genetics -- Research; Genomics; Electronic journals; Periodical; Periodicals; Fulltext; Internet Resources; Periodicals; 572.8
• DOI: 10.1534/g3.119.400831
• Languages: English
• ISSNs: 2160-1836

Abstract

Abstract: The black yeast-like fungus Arthrocladium fulminans is known from strains that cause severe and eventually fatal disseminated infections in immunocompromised patients. Given the dramatic outcome of this clinical case, it is essential to understand the virulence potential of this species. The fungus is a member of the family Trichomeriaceae, at some phylogenetic distance from the Herpotrichiellaceae where most infectious fungi in the order Chaetothyriales are located. Main ecological preferences among Trichomeriaceae include colonization of exposed inert surfaces. Currently, black yeasts genomes that are available in public databases cover members of the families Herpotrichiellaceae and Cyphellophoraceae . In the present report, we sequenced the genome of the first member and only clinical representative of the family Trichomeriaceae .