Amphiphilic Indoles as Efficient Phase‐Transfer Catalysts for Bromination in Water. Issue 12 (13th May 2022)

• Record Type: Journal Article
• Authors: Zhang, Qingyu; Xu, Yongyuan; Liang, Xiaochen; Ke, Zhihai
• Is Part Of: ChemSusChem. Volume 15:Issue 12(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-05-13
• Subjects: bromination -- green chemistry -- halogenation -- indoles -- phase-transfer catalysis; Green chemistry -- Periodicals; Sustainable engineering -- Periodicals; Chemistry -- Periodicals; Chemical engineering -- Periodicals; 660
• DOI: 10.1002/cssc.202200574
• Languages: English
• ISSNs: 1864-5631

Abstract

Abstract: Brominated compounds are important, but they are usually prepared in organic solvents. Here, efficient amphiphilic indole‐based phase‐transfer organocatalysts were developed for environmentally benign bromination reactions in water. As test reactions, hydroxybromination of olefins and aromatic bromination could be conducted in a greener and more sustainable manner compared with methods using organic solvents, producing the corresponding bromides in good yields. Some pure products could be obtained without column chromatography. Abstract : Just add water : Under the phase‐transfer catalysis of amphiphilic indoles, an efficient and environmentally friendly bromination in water is developed. As test reactions, hydroxybromination of olefins and aromatic bromination are conducted.