Advances in HIV Eradication Strategies. Issue 2 (3rd June 2022)

• Record Type: Journal Article
• Authors: Mei, Qingmin; Wang, Wei; Wu, Jianjun; Gao, Yong
• Editors: Shao, Yiming
• Is Part Of: Infectious microbes & diseases. Volume 4:Issue 2(2022)
• Page Start: 64
• Page End: 70
• Publication Date: 2022-06-03
• Subjects: HIV -- latent reservoir -- latency reversing agents; Medical microbiology -- Periodicals; Communicable diseases -- Periodicals; Communicable diseases; Medical microbiology; Periodicals; 616
• DOI: 10.1097/IM9.0000000000000088
• Languages: English
• ISSNs: 2096-7241

Abstract

Abstract : Abstract: Although the advent of combination antiretroviral therapy can efficiently suppress human immunodeficiency virus (HIV) replication, a complete cure for HIV infection cannot be achieved due to the existence of latent viral reservoirs. In recent years, investigation of HIV cure strategies has become a hot topic in the field. In this article, we review the major barriers to HIV cure, compare the progress and challenges of non-specific and specific latent reversal agents in curing HIV, and discuss possible solutions to the current problems.