Sustainable and green synthesis of novel acid phosphatase mediated platinum nanoparticles (ACP-PtNPs) and investigation of its in vitro antibacterial, antioxidant, hemolysis and photocatalytic activities. Issue 3 (June 2022)

• Record Type: Journal Article
• Authors: Rehman, Khalil ur; Khan, Shahid Ullah; Tahir, Kamran; Zaman, Umber; Khan, Dilfaraz; Nazir, Sadia; Khan, Wasim Ullah; Khan, Muhammad Imran; Ullah, Kalim; Anjum, Syed Ishtiaq; Bibi, Robina
• Is Part Of: Journal of environmental chemical engineering. Volume 10:Issue 3(2022)
• Publication Date: 2022-06
• Subjects: Biofabrication -- Platinum nanoparticles -- Photocatalytic activity -- RBCs toxicity -- And DPPH radicals; Chemical engineering -- Environmental aspects -- Periodicals; Environmental engineering -- Periodicals; Chemical engineering -- Environmental aspects; Environmental engineering; Periodicals; 660.0286
• DOI: 10.1016/j.jece.2022.107623
• Languages: English
• ISSNs: 2213-2929

Abstract

Abstract: Clean water is a worldwide major problem and several conventional strategies are accompanied with a number of drawbacks. To overcome this problem, new methods and materials have been introduced to address the problem of water purification. Platinum nanoparticles (PtNPs) are a fascinating and appealing research area as they are a series of effective environmental and biomedical applications. The present study is the first to report an immediate, cost-effective, and eco-begin synthesis of ACP-PtNPs using acid phosphatase of Rumex dentatus seeds extract. Acid phosphatase performed an imperative role in the stability, and capping of ACP-PtNPs. The ACP-PtNPs were characterized by different techniques, including UV–visible spectroscopy, XRD, FTIR, XPS, HRTEM, EDS, SEM and DLS analysis. ACP-PtNPs were brown-colored and mostly spherical in shape, with ultra-small particle size (1–7 nm). The onset of a plasmon peak at 295 nm confirmed the formation of ACP-PtNPs. The as-prepared nanoparticles were tested for the photocatalytic degradation of methylene blue (MB) under visible light irradiation. The results showed that ACP-PtNPs exhibited remarkable photocatalytic efficiency by degrading 99% of MB only in 28 min. ACP-PtNPs were also showed strong photoinhibition efficiency against gram negative bacteria. ACP-PtNPs were found to be harmless to normal healthy RBCs in the cytotoxicity investigation. Furthermore, ACP-PtNPs also possessed superb antioxidant activity whereby effectively scavenging 88% of stable and harmful 1, 1-diphenyl-2-picryl-hydrazil (DPPH) radical. These exceptional photocatalytic and biomedical activities may be attributed to the trivial size and large surface area of ACP-PtNPs. Graphical Abstract: Synthesis, characterizations, biomedical and photocatalytic applications of ACP-PtNPs ga1 Highlights: Synthesis of novel acid phosphatase mediated ACP-PtNPs through a green synthetic approach. ACP-PtNPs were tested for the photodegradation of methylene blue. PtNPs have significant antibacterial activity against multidrug resistant bacteria (i.e E.coli). Toxicity against red blood cells (RBCs). DPPH scavenging activity was studied.