Consumption of industrial processed foods and risk of premenopausal breast cancer among Latin American women: the PRECAMA study. Issue 1 (4th January 2022)

• Record Type: Journal Article
• Authors: Romieu, Isabelle; Khandpur, Neha; Katsikari, Aikaterini; Biessy, Carine; Torres-Mejía, Gabriela; Ángeles-Llerenas, Angélica; Alvarado-Cabrero, Isabel; Sánchez, Gloria Inés; Maldonado, Maria Elena; Porras, Carolina; Rodriguez, Ana Cecilia; Garmendia, Maria Luisa; Chajés, Vèronique; Aglago, Elom K; Porter, Peggy L; Lin, MingGang; His, Mathilde; Gunter, Marc J; Huybrechts, Inge; Rinaldi, Sabina
• Other Names: author non-byline.; Tejeda Jenny author non-byline.; Navarro Edgar author non-byline.; Jaramillo Roberto author non-byline.; Cortes Yorlany Rodas author non-byline.; Angel Alberto author non-byline.; Ossa Carlos Andres author non-byline.; Arias William H author non-byline.; Bedoya Gabriel author non-byline.; Cock-Rada Alicia author non-byline.; Herazo Fernando author non-byline.; Díaz-Yunez Israel author non-byline.; Hernández Angel author non-byline.; Cortes Bernal author non-byline.; Gonzalez Paula author non-byline.; Ocampo Rebecca author non-byline.; Guillen Diego author non-byline.; Loría Viviana author non-byline.; Moyano Leonor author non-byline.; Soto Jose Luis author non-byline.; Donato Elizabeth author non-byline.; Guenthoer Jamie author non-byline.; Donn Thomas author non-byline.; Wirtala Kelly author non-byline.; Loucks Hailey author non-byline.
• Is Part Of: BMJ nutrition, prevention & health. Volume 5:Issue 1(2022)
• Page Start: 1
• Page End: 9
• Publication Date: 2022-01-04
• Subjects: nutrition assessment; Nutrition -- Periodicals; Health behavior -- Periodicals; Lifestyles -- Periodicals; 613
• DOI: 10.1136/bmjnph-2021-000335
• Languages: English
• ISSNs: 2516-5542

Abstract

Abstract : Ultra-processed food intake has been linked to an increased risk of breast cancer in Western populations. No data are available in the Latin American population although the consumption of ultra-processed foods is increasing rapidly in this region. We evaluated the association of ultra-processed food intake to breast cancer risk in a case–control study including 525 cases (women aged 20–45 years) and 525 matched population-based controls from Chile, Colombia, Costa Rica and Mexico. The degree of processing of foods was classified according to the NOVA classification. Overall, the major contributors to ultra-processed food intake were ready-to-eat/heat foods (18.2%), cakes and desserts (16.7%), carbonated and industrial fruit juice beverages (16.7%), breakfast cereals (12.9%), sausages and reconstituted meat products (12.1%), industrial bread (6.1%), dairy products and derivatives (7.6%) and package savoury snacks (6.1%). Ultra-processed food intake was positively associated with the risk of breast cancer in adjusted models (OR T3-T1 =1.93; 95% CI=1.11 to 3.35). Specifically, a higher risk was observed with oestrogen receptor positive breast cancer (ORT3-T1 =2.44, (95% CI=1.01 to 5.90, P-trend=0.049), while no significant association was observed with oestrogen receptor negative breast cancer (ORT3-T1 =1.87, 95% CI=0.43 to 8.13, P-trend=0.36). Our findings suggest that the consumption of ultra-processed foods might increase the risk of breast cancer in young women in Latin America. Further studies should confirm these findings and disentangle specific mechanisms relating ultra-processed food intake and carcinogenic processes in the breast.