Β‐Cyclodextrin‐Based Nanocomposite Derivatives: State of the Art in Synthesis, Characterization and Application in Molecular Recognition. Issue 22 (9th June 2022)

• Record Type: Journal Article
• Authors: Tarannum, Nazia; Kumar, Deepak; Kumar, Nitin
• Is Part Of: ChemistrySelect. Volume 7:Issue 22(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-06-09
• Subjects: β-cyclodextrin -- Molecular recognition -- MIPs -- Nanocomposites -- Nanostructures; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202200140
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: This review describes the synthesis of nanocomposite derivatives based on β‐cyclodextrin (β‐CD) using silver nanoparticles (NPs), gold NPs, magnetic NPs, carbon nanotubes, nanosheets, carbon dots and graphene oxide NPs. These nanocomposites were prepared by green synthesis method, chemical method, reduction method, thermal reduction, ultrasonication method and hydrothermal method. β‐CD is cyclic oligosaccharide consisting of seven glucose units linked by 1, 4‐α‐glycosidic bonds. Its external surface is hydrophilic due to the substantial hydroxyl groups, and the interior is hydrophobic. β‐CD are useful in nanocomposites and metallic NPs because they provide nanoplatforms for biocompatibility. β‐CD is commonly used to change NPs because of their excellent biocompatibility, amphipathic properties and for enhancing the morphological and chemical features of nanocomposites. Thus, nanostructured materials based on β‐CD may enhance the potential for molecular recognition property which is a natural phenomenon and fundamentally important in chemistry and biology. The most important area in molecular recognition research is design and synthesis of model receptors (hosts) to recognize substrates (guests) of biochemical significance to mimic biological events. Because NPs have a high surface‐to‐volume ratio when combined with molecularly imprinted polymers (MIPs). This review briefs the application and characterizations of β‐CD based nanocomposites derivatives in molecular recognition. Abstract : β‐CD based nanomaterials have been used as composites in MIPs, because β‐CD based nanocomposites which provides larger surface area as well as stability toward specific intended use which exhibit unique properties such as susceptibility, robust mechanical strength, high surface to volume ratio, electrical and optical properties for analyte determination, good dispersion, easy removal of the template, surface modification, functionalization and handling capacity. It is now used not only for bioanalysis as well as in environmental applications.