Quantum dots against SARS‐CoV‐2: diagnostic and therapeutic potentials. Issue 7 (4th February 2022)

• Record Type: Journal Article
• Authors: Rabiee, Navid; Ahmadi, Sepideh; Soufi, Ghazaleh Jamalipour; Hekmatnia, Ali; Khatami, Mehrdad; Fatahi, Yousef; Iravani, Siavash; Varma, Rajender S
• Is Part Of: Journal of chemical technology & biotechnology. Volume 97:Issue 7(2022)
• Page Start: 1640
• Page End: 1654
• Publication Date: 2022-02-04
• Subjects: biochemical engineering -- bioprocesses -- disinfection -- removal; Biotechnology -- Periodicals; Chemistry, Technical -- Periodicals; Chemical engineering -- Periodicals; Industries -- Environmental aspects -- Periodicals; 660
• DOI: 10.1002/jctb.7036
• Languages: English
• ISSNs: 0268-2575

Abstract

Abstract: The application of quantum dots (QDs) for detecting and treating various types of coronaviruses is very promising, as their low toxicity and high surface performance make them superior among other nanomaterials; in conjugation with fluorescent probes they are promising semiconductor nanomaterials for the detection of various cellular processes and viral infections. In view of the successful results for inhibiting SARS‐CoV‐2, functional QDs could serve eminent role in the growth of safe nanotherapy for the cure of viral infections in the near future; their large surface areas help bind numerous molecules post‐synthetically. Functionalized QDs with high functionality, targeted selectivity, stability and less cytotoxicity can be employed for highly sensitive co‐delivery and imaging/diagnosis. Besides, due to the importance of safety and toxicity issues, QDs prepared from plant sources (e.g. curcumin) are much more attractive, as they provide good biocompatibility and low toxicity. In this review, the recent developments pertaining to the diagnostic and inhibitory potentials of QDs against SARS‐CoV‐2 are deliberated including important challenges and future outlooks. © 2022 Society of Chemical Industry (SCI).