Chemical constituents of Impatiens chapaensis Tard. and their α-glucosidase inhibition activities. Issue 12 (15th June 2022)

• Record Type: Journal Article
• Authors: Linh, Nguyen Thi Thuy; Thuy, Trinh Thi; Tam, Nguyen Thanh; Cham, Ba Thi; Tam, Khieu Thi; Sa, Nguyen Hoang; Thao, Do Thi; Chinh, Vu Tien; Anh, Nguyen Thi Hoang
• Is Part Of: Natural product research. Volume 36:Issue 12(2022)
• Page Start: 3229
• Page End: 3233
• Publication Date: 2022-06-15
• Subjects: Impatiens chapaensis -- Balsaminaceae -- flavonoid glycoside -- sesquiterpene -- neolignan glycoside; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2021.1956923
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Sixteen compounds (1 -16 ) were isolated from Impatiens chapaensis . Chemical structures were determined by spectroscopic analyses and comparisons with previously published data. This report is the first to identify compounds 1, 5–7, 10, 12–14, and 16 from the genus Impatiens. Seven chosen isolates (5, 7, 10, 11, 12, 15, and 16 ) were submitted for α -glucosidase inhibition assays with acarbose as the positive control (IC50 = 227.14 ± 13.71 µM). Flavonoid 5 exhibited a significant inhibitory effect (IC50 = 101.00 ± 9.01 µM). Graphical Abstract: UF0001