Brain plasticity after rehabilitation in a severe case of artery of Percheron stroke assessed with multimodal MR imaging. Issue 2 (4th March 2022)

• Record Type: Journal Article
• Authors: Tavazzi, E.; Bergsland, N.; Pirastru, A.; Pelizzari, L.; Cazzoli, M.; Saibene, F.L.; Navarro, J.S.; Farina, E.; Comanducci, A; Cecconi, P.; Baglio, F.
• Is Part Of: Neurocase. Volume 28:Issue 2(2022)
• Page Start: 194
• Page End: 198
• Publication Date: 2022-03-04
• Subjects: Artery of percheron -- stroke -- fMRI -- MRI -- neurorehabilitation; Neurology -- Periodicals; Neuropsychology -- Case Report; Mental Disorders -- Case Report; Nervous System Diseases -- Case Report; 616.8
• DOI: 10.1080/13554794.2022.2062249
• Languages: English
• ISSNs: 1355-4794

Abstract

ABSTRACT: Artery of Percheron (AOP) stroke is a rare event. We describe an AOP stroke involving both thalami and the midbrain, resulting in a multifunctional clinical impairment. Intensive inpatient multidisciplinary rehabilitation favored the recovery of motor deficits, together with the improvement of cognitive dysfunctions. MRI assessment in the chronic post-stroke phase showed structural and functional reorganization in response to the extended thalamic tissue damage and absence of revascularization. Thalamo-cortical networks involving frontal and prefrontal regions, as well as parietal areas were disrupted, whereas increased functional thalamo-occipital connectivity was found. This report sheds light on brain reorganization following AOP stroke after rehabilitation..