Back Cover: Advanced Real‐Time Process Analytics for Multistep Synthesis in Continuous Flow (Angew. Chem. Int. Ed. 15/2021). Issue 15 (8th March 2021)

• Record Type: Journal Article
• Authors: Sagmeister, Peter; Lebl, René; Castillo, Ismael; Rehrl, Jakob; Kruisz, Julia; Sipek, Martin; Horn, Martin; Sacher, Stephan; Cantillo, David; Williams, Jason D.; Kappe, C. Oliver
• Is Part Of: Angewandte Chemie international edition. Volume 60:Issue 15(2021)
• Page Start: 8556
• Page End: 8556
• Publication Date: 2021-03-08
• Subjects: flow chemistry -- multistep synthesis -- process analytical technologies -- process control -- real-time analysis; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.202102668
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : Advanced process analytics are becoming an increasingly important part of continuous flow chemistry. In their Research Article on page 8139, Jason D. Williams, C. Oliver Kappe and co‐workers describe the use of four different process analytical technologies, controlled by one central system, in a multistep continuous flow process. Advanced data processing methods, including artificial intelligence, are used to accurately quantify up to nine process species in real time, toward self‐optimization and model predictive control applications.