Clinical characteristic and epidemiological features of SARS CoV‐2 disease patients from a COVID‐19 designated hospital in New Delhi. Issue 4 (22nd January 2021)

• Record Type: Journal Article
• Authors: Saxena, Sonal; Manchanda, Vikas; Sagar, Tanu; Nagi, Nazia; Siddiqui, Oves; Yadav, Abhishek; Arora, Nitin; Hasan, Faria; Meena, Kavita; Bharti, Pradeep; Rana, Neha; Hayat, Sikander; Tuteja, Sanchita; Yadav, Ajeet; Puri, Devyani; Pumma, Palak; Khyati, ; Arora, Ananya; Jainandra, ; Shreya, Sunidhi; Kumar, Suresh; Sharma, Nandini
• Other Names: Luo Guangxiang (George) guestEditor.; Ly Hinh guestEditor.; Gao Shou‐Jiang guestEditor.
• Is Part Of: Journal of medical virology. Volume 93:Issue 4(2021)
• Page Start: 2487
• Page End: 2492
• Publication Date: 2021-01-22
• Subjects: coronavirus disease -- COVID‐19 -- SARS‐CoV‐2; Virology -- Periodicals; 616
• DOI: 10.1002/jmv.26777
• Languages: English
• ISSNs: 0146-6615

Abstract

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2) infection is rapidly evolving as a serious global pandemic. The present study describes the clinical characteristics of SARS CoV‐2 infection patients. The samples were subjected to reverse‐transcription polymerase chain reaction or Rapid Antigen test for diagnosis of SARS CoV‐2. A cohort of 3745 patients with confirmed diagnosis of SARS CoV‐2 infection in a tertiary care center in New Delhi, India were included in this study. Data were collected from offline and online medical records over a period of 6 months. Amongst 3745 SARS CoV‐2 infected patients, 2245 (60%) were symptomatic and 1500 (40%) were asymptomatic. Most common presenting symptom was cough (49.3%) followed febrile episodes (47.1%), breathlessness (42.7%), and sore throat (35.1%). Cough along with breathlessness (24.1) was the most common combination of symptoms followed by fever with cough (22.7). The most common comorbidity found among symptomatic group was diabetes (42.5%) followed by hypertension (21.4%) and chronic kidney disease (18%). Comorbidities like diabetes mellitus, chronic diseases of lungs, heart, and kidneys were found to be common in symptomatic group and this was found to be statistically significant ( p < .05). COVID‐19 is an evolving disease and data from our study help in understanding the clinic‐epidemiological profile of patients. Highlights: Article describes data from a cohort of 3745 patients with confirmed diagnosis of SARS CoV ‐2 infection. Most common presenting symptom was cough (49.3%) followed febrile episodes (47.1%), breathlessness (42.7%) and sore throat (35.1%). Cough along with breathlessness (24.1) was the most common combination of symptoms followed by fever with cough (22.7). The most common comorbidity found among symptomatic group was diabetes (42.5%) followed by hypertension (21.4%) and chronic kidney disease (18%). Comorbidities like diabetes mellitus, chronic diseases of lungs, heart and kidneys were found to be statistically significant ( p < .05).